# Recombination activating gene 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21496783](https://www.wikidata.org/wiki/Q21496783)  
**Source**: https://4ort.xyz/entity/recombination-activating-gene-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P21784)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
5. [The RAG1 N-terminal domain is an E3 ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
6. [A PHD finger motif in the C terminus of RAG2 modulates recombination activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
7. [RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
8. [The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
9. [Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
10. [Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
11. [Crystal structure of the V(D)J recombinase RAG1–RAG2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
13. [A novel testis-specific RAG2-like protein, Peas: its expression in pachytene spermatocyte cytoplasm and meiotic chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
14. [Constitutive Bcl-2 expression during immunoglobulin heavy chain-promoted B cell differentiation expands novel precursor B cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
15. [RAG-1-deficient mice have no mature B and T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
16. [A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
17. [The Earliest T Lineage–Committed Cells Depend on IL-7 for Bcl-2 Expression and Normal Cell Cycle Progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
18. [Spi-B can functionally replace PU.1 in myeloid but not lymphoid development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
19. [Influence of apoA-I and apoE on the formation of serum amyloid A-containing lipoproteins in vivo and in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
20. [Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
21. [RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21784&geneProductId=UniProtKB:P21784)
22. [RAG-1-deficient mice have no mature B and T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21784&geneProductId=UniProtKB:P21784)
23. [RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21784&geneProductId=UniProtKB:P21784)
24. [RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
25. [RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
26. [Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
27. [RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21784)
28. ensembl Release 106