# Recombination activating 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21496781](https://www.wikidata.org/wiki/Q21496781)  
**Source**: https://4ort.xyz/entity/recombination-activating-1-q21496781


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15919)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
5. [Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
6. [A WW-like module in the RAG1 N-terminal domain contributes to previously unidentified protein-protein interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
7. [Crystal structure of the V(D)J recombinase RAG1–RAG2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
8. [Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
9. [The RAG1 N-terminal domain is an E3 ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
10. [The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
11. [Autoubiquitylation of the V(D)J recombinase protein RAG1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
12. [Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
13. [Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
15. [Expression and V(D)J recombination activity of mutated RAG-1 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
16. [TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
17. [HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
18. [The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
19. [A novel testis-specific RAG2-like protein, Peas: its expression in pachytene spermatocyte cytoplasm and meiotic chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
20. [RAG-1-deficient mice have no mature B and T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
21. [RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
22. [Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
23. [Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
24. [RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15919)
25. ensembl Release 106