# RB transcriptional corepressor 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111463](https://www.wikidata.org/wiki/Q21111463)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Retinoblastoma_protein)  
**Source**: https://4ort.xyz/entity/rb-transcriptional-corepressor-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P06400)
3. Q20641742
4. [The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
6. [Negative modulation of androgen receptor transcriptional activity by Daxx](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
7. [HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
8. [Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
9. [The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
10. [A novel Rb- and p300-binding protein inhibits transactivation by MyoD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
11. [Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
12. [Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
13. [Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
14. [Methylation of the retinoblastoma tumor suppressor by SMYD2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
15. [Phosphorylated retinoblastoma protein stimulates DNA polymerase α](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
16. [LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
17. [Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
18. [Physical interaction between pRb and cdk9/cyclinT2 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
19. [NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
20. [The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
21. [L3MBTL1, a histone-methylation-dependent chromatin lock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
22. [Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
23. [The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
24. [Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
25. [RBP95, a novel leucine zipper protein, binds to the retinoblastoma protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
26. [The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
27. [A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
28. [Association of Human Purα with the Retinoblastoma Protein, Rb, Regulates Binding to the Single-stranded DNA Purα Recognition Element](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
29. [Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
30. [Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
31. [Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
32. [p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
33. [Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
34. [Binding of an interferon-inducible protein (p202) to the retinoblastoma protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
35. [Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
36. [Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
37. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
38. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
39. [p53 family members in myogenic differentiation and rhabdomyosarcoma development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
40. [Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
41. [Shigella flexneri type III secretion system effectors OspB and OspF target the nucleus to downregulate the host inflammatory response via interactions with retinoblastoma protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
42. [Structure of the oncoprotein gankyrin in complex with S6 ATPase of the 26S proteasome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
43. [HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
44. [Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
45. [LEDGF (p75) promotes DNA-end resection and homologous recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
46. [Rb–Raf-1 Interaction Disruptor RRD-251 Induces Apoptosis in Metastatic Melanoma Cells and Synergizes with Dacarbazine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
47. [Proapoptotic function of the retinoblastoma tumor suppressor protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
48. [HAUSP, a novel deubiquitinase for Rb – MDM2 the critical regulator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
49. [Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)
50. [Mapping a dynamic innate immunity protein interaction network regulating type I interferon production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400)