Ras homolog, mTORC1 binding
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: Frank Ullrich
additional property: PropertyValue
  property ID: P361
  value: GTP-binding protein Rheb
additional property: PropertyValue
  property ID: P361
  value: P-loop containing nucleoside triphosphate hydrolase
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P527
  value: small GTP-binding protein domain
additional property: PropertyValue
  property ID: P637
  value: NP_037348
additional property: PropertyValue
  property ID: P637
  value: XP_038963083
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: GTPase activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: Golgi membrane
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: endoplasmic reticulum
additional property: PropertyValue
  property ID: P682
  value: signal transduction
additional property: PropertyValue
  property ID: P682
  value: small GTPase mediated signal transduction
additional property: PropertyValue
  property ID: P682
  value: positive regulation of TOR signaling
additional property: PropertyValue
  property ID: P702
  value: Rheb
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000063915
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 12
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 12
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q62639
    source count: 1
    confidence: 0.2
    value label: Frank Ullrich
  P361:
    value: Q43921663
    source count: 1
    confidence: 0.2
    value label: GTP-binding protein Rheb
  P361:
    value: Q24726930
    source count: 1
    confidence: 0.2
    value label: P-loop containing nucleoside triphosphate hydrolase
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83135274
    source count: 1
    confidence: 0.2
    value label: Small GTP-binding protein domain family
  P527:
    value: Q24725166
    source count: 1
    confidence: 0.2
    value label: small GTP-binding protein domain
  P637:
    value: NP_037348
    source count: 1
    confidence: 0.2
  P637:
    value: XP_038963083
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14865041
    source count: 2
    confidence: 0.4
    value label: GTPase activity
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14863341
    source count: 3
    confidence: 0.6
    value label: GTP binding
  P680:
    value: Q14907895
    source count: 1
    confidence: 0.2
    value label: GDP binding
  P681:
    value: Q14598778
    source count: 1
    confidence: 0.2
    value label: Golgi membrane
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q79927
    source count: 1
    confidence: 0.2
    value label: endoplasmic reticulum
  P681:
    value: Q14329032
    source count: 1
    confidence: 0.2
    value label: endoplasmic reticulum membrane
  P681:
    value: Q83181
    source count: 1
    confidence: 0.2
    value label: Golgi apparatus
  P682:
    value: Q828130
    source count: 1
    confidence: 0.2
    value label: signal transduction
  P682:
    value: Q14865044
    source count: 1
    confidence: 0.2
    value label: small GTPase mediated signal transduction
  P682:
    value: Q14331008
    source count: 2
    confidence: 0.4
    value label: positive regulation of TOR signaling
  P682:
    value: Q14862277
    source count: 1
    confidence: 0.2
    value label: regulation of neuronal synaptic plasticity
  P682:
    value: Q47009040
    source count: 2
    confidence: 0.4
    value label: regulation of postsynapse organization
  P702:
    value: Q24384279
    source count: 1
    confidence: 0.2
    value label: Rheb

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

value: ENSRNOP00000063915
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-05-09

source: Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
stated in qid: Q24535576
retrieved: 2019-02-14

source: Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent
stated in qid: Q28262376
retrieved: 2019-05-09

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-05-09

source: Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites
stated in qid: Q28569134
retrieved: 2019-05-09

source: Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex
stated in qid: Q40187301
retrieved: 2019-05-09

source: rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein
stated in qid: Q24316714
retrieved: 2019-05-09

source: Rheb Inhibits Beiging of White Adipose Tissue via PDE4D5-Dependent Downregulation of the cAMP-PKA Signaling Pathway
stated in qid: Q48289477
retrieved: 2019-05-09

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2021-11-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2021-09-07

source: ensembl Release 104
stated in qid: Q106833387

wikidata id: Q28562868
domain: protein
level: standard
html url: https://4ort.xyz/entity/ras-homolog-mtorc1-binding
markdown url: https://4ort.xyz/entity/ras-homolog-mtorc1-binding.md
facts url summary: https://4ort.xyz/entity/ras-homolog-mtorc1-binding/facts.json
facts url standard: https://4ort.xyz/entity/ras-homolog-mtorc1-binding/facts.json
facts url full: https://4ort.xyz/entity/ras-homolog-mtorc1-binding/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-25T10:13:48.628533Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:59:55.134900+00:00Z