# Ras homolog family member A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7276719](https://www.wikidata.org/wiki/Q7276719)  
**Source**: https://4ort.xyz/entity/ras-homolog-family-member-a


## References

1. UniProt
2. [BioGRID](https://thebiogrid.org/news/227)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61586)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/C9JNR4)
5. Q20641742
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:C9JNR4)
8. [BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
9. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P61586)
10. [TIM, a Dbl-related protein, regulates cell shape and cytoskeletal organization in a Rho-dependent manner](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P61586)
11. [Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P61586)
12. [The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
13. [The armadillo protein p0071 regulates Rho signalling during cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
14. [Fam65b Is a New Transcriptional Target of FOXO1 That Regulates RhoA Signaling for T Lymphocyte Migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
15. [The Rho Target PRK2 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
16. [Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
17. [Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
18. [RHO binding to FAM65A regulates Golgi reorientation during cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
19. [Front Signal-Dependent Accumulation of RHOA Inhibitor FAM65B at Leading Edges Polarizes Neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
20. [Identification, characterization, and functional analysis of heart-specific myosin light chain phosphatase small subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
21. [The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
22. [Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
23. [EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
24. [A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
25. [Activation of a bacterial virulence protein by the GTPase RhoA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
26. [A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
27. [The role of ezrin-associated protein network in human sperm capacitation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
28. [Arachidonic acid stimulates formation of a novel complex containing nucleolin and RhoA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
29. [WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
30. [Plk4 is required for cytokinesis and maintenance of chromosomal stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
31. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
32. [A Salmonella typhimurium-translocated glycerophospholipid:cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
33. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
34. [Effect of cancer-associated mutations in the PlexinB1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
35. [Distinct biological activities of C3 and ADP‐ribosyltransferase‐deficient C3‐E174Q](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
36. [Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
37. [Prenylated Rab acceptor protein is a receptor for prenylated small GTPases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
38. [Structural basis for the selective activation of Rho GTPases by Dbl exchange factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
39. [Structural insights into the interaction of ROCKI with the switch regions of RhoA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
40. [An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
41. [How RhoGDI binds Rho](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
42. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
43. [MgF(3)(-) as a transition state analog of phosphoryl transfer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
44. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
45. [Advanced glycation end products increase endothelial permeability through the RAGE/Rho signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
46. [Inter-domain motions of the N-domain of the KdpFABC complex, a P-type ATPase, are not driven by ATP-induced conformational changes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
47. [RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
48. [RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
49. [p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)
50. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61586)