# Ras homolog family member A

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561735](https://www.wikidata.org/wiki/Q28561735)  
**Source**: https://4ort.xyz/entity/ras-homolog-family-member-a-q28561735


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61589)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
5. [Distribution of Rho family GTPases in the adult rat hippocampus and cerebellum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
6. [Upregulation of small GTPase RhoA in the basilar artery from diabetic (mellitus) rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
7. [Extra-nuclear activation of progesterone receptor in regulating arterial smooth muscle cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
9. [Dysbindin is a potent inducer of RhoA-SRF-mediated cardiomyocyte hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
10. [Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
11. [Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
12. [Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
13. [Cellular regulation of basal tone in internal anal sphincter smooth muscle by RhoA/ROCK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
14. [Activated RHOA and peripheral axon regeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
15. [Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
16. [Local, persistent activation of Rho GTPases during plasticity of single dendritic spines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
17. [Actin cytoskeleton dynamics promotes leptin-induced vascular smooth muscle hypertrophy via RhoA/ROCK- and phosphatidylinositol 3-kinase/protein kinase B-dependent pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
18. [Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
19. [RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
20. [Small GTPase Rin induces neurite outgrowth through Rac/Cdc42 and calmodulin in PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
21. [The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
22. [Nogo enhances the adhesion of olfactory ensheathing cells and inhibits their migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
23. [The functional consequence of RhoA knockdown by RNA interference in rat cerebral arteries](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
24. [Rho mediates calcium-dependent activation of p38alpha and subsequent excitotoxic cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
25. [RhoA regulation of NF-kappaB activation is mediated by COX-2-dependent feedback inhibition of IKK in kidney epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
26. [Differential effects of phenylalanine on Rac1, Cdc42, and RhoA expression and activity in cultured cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
27. [Phenylalanine activates the mitochondria-mediated apoptosis through the RhoA/Rho-associated kinase pathway in cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
28. [Lysophosphatidic acid rescues RhoA activation and phosphoinositides levels in astrocytes exposed to ethanol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
29. [Ethanol impairs Rho GTPase signaling and differentiation of cerebellar granule neurons in a rodent model of fetal alcohol syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
30. [RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
31. [Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
32. [RhoA regulates dendrite branching in hippocampal neurons by decreasing cypin protein levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
33. [Glucocorticoids ameliorate antigen-induced bronchial smooth muscle hyperresponsiveness by inhibiting upregulation of RhoA in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
34. [Regulation of T-type calcium channels by Rho-associated kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
35. [Mutant Huntingtin Alters Cell Fate in Response to Microtubule Depolymerization via the GEF-H1-RhoA-ERK Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61589)
36. ensembl Release 104