Ras homolog family member A
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: P-loop containing nucleoside triphosphate hydrolase
additional property: PropertyValue
  property ID: P361
  value: small GTPase Rho
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P527
  value: small GTP-binding protein domain
additional property: PropertyValue
  property ID: P637
  value: NP_001300890
additional property: PropertyValue
  property ID: P637
  value: NP_001300891
additional property: PropertyValue
  property ID: P637
  value: NP_058082
additional property: PropertyValue
  property ID: P638
  value: 4F38
additional property: PropertyValue
  property ID: P638
  value: 3TVD
additional property: PropertyValue
  property ID: P680
  value: GTPase activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P681
  value: ruffle membrane
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: negative regulation of neuron apoptotic process
additional property: PropertyValue
  property ID: P682
  value: response to amino acid
additional property: PropertyValue
  property ID: P682
  value: regulation of neuron projection development
additional property: PropertyValue
  property ID: P702
  value: Rhoa
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000007959
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000141572
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000141967
confidence:
  popularity graph score:
    score: 0.008
    score pct: 1
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 57
      unique citations norm: 0.022
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 57
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9QUI0
    source count: 1
    confidence: 0.2
  P361:
    value: Q24726930
    source count: 1
    confidence: 0.2
    value label: P-loop containing nucleoside triphosphate hydrolase
  P361:
    value: Q29564364
    source count: 1
    confidence: 0.2
    value label: small GTPase Rho
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83135274
    source count: 1
    confidence: 0.2
    value label: Small GTP-binding protein domain family
  P527:
    value: Q24725166
    source count: 1
    confidence: 0.2
    value label: small GTP-binding protein domain
  P637:
    value: NP_001300890
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001300891
    source count: 1
    confidence: 0.2
  P637:
    value: NP_058082
    source count: 1
    confidence: 0.2
  P638:
    value: 4F38
    source count: 1
    confidence: 0.2
  P638:
    value: 3TVD
    source count: 1
    confidence: 0.2
  P680:
    value: Q14865041
    source count: 7
    confidence: 1.0
    value label: GTPase activity
  P680:
    value: Q167149
    source count: 11
    confidence: 1.0
    value label: protein binding
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14863341
    source count: 5
    confidence: 1.0
    value label: GTP binding
  P680:
    value: Q21155032
    source count: 1
    confidence: 0.2
    value label: Rho GDP-dissociation inhibitor binding
  P681:
    value: Q220599
    source count: 4
    confidence: 0.8
    value label: cytosol
  P681:
    value: Q14883311
    source count: 1
    confidence: 0.2
    value label: ruffle membrane
  P681:
    value: Q39572
    source count: 1
    confidence: 0.2
    value label: mitochondrion
  P681:
    value: Q154626
    source count: 1
    confidence: 0.2
    value label: cytoskeleton
  P681:
    value: Q40260
    source count: 1
    confidence: 0.2
    value label: nucleus
  P682:
    value: Q14820618
    source count: 1
    confidence: 0.2
    value label: negative regulation of neuron apoptotic process

value: Q14860834
source count: 1
confidence: 0.2
value label: response to amino acid

value: Q14878350
source count: 1
confidence: 0.2
value label: regulation of neuron projection development

value: Q14852032
source count: 1
confidence: 0.2
value label: regulation of transcription by RNA polymerase II

value: Q14864218
source count: 1
confidence: 0.2
value label: positive regulation of translation

value: Q15331491
source count: 1
confidence: 0.2
value label: Rhoa

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000007959
source count: 1
confidence: 0.2

value: ENSMUSP00000141572
source count: 1
confidence: 0.2

value: ENSMUSP00000141967
source count: 1
confidence: 0.2

source: Small GTP-binding proteins and the regulation of the actin cytoskeleton
stated in qid: Q28586463
retrieved: 2017-09-16

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-16

source: Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA
stated in qid: Q22253269
retrieved: 2017-09-16

source: Vav GEFs are required for beta2 integrin-dependent functions of neutrophils
stated in qid: Q28590406
retrieved: 2017-09-16

source: Muscle-specific signaling mechanism that links actin dynamics to serum response factor
stated in qid: Q24520637
retrieved: 2017-09-16

source: The Rho Target PRK2 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells
stated in qid: Q24304376
retrieved: 2019-02-14

source: Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
stated in qid: Q29347270
retrieved: 2019-02-14

source: Front Signal-Dependent Accumulation of RHOA Inhibitor FAM65B at Leading Edges Polarizes Neutrophils
stated in qid: Q27342099
retrieved: 2019-02-14

source: Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression
stated in qid: Q28512285
retrieved: 2019-02-14

source: IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade
stated in qid: Q28510385
retrieved: 2019-02-14

source: p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin
stated in qid: Q24316148
retrieved: 2019-02-14

source: EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation
stated in qid: Q24304584
retrieved: 2019-02-14

source: High blood pressure arising from a defect in vascular function.
stated in qid: Q36638652
retrieved: 2019-02-14

source: The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
stated in qid: Q24337165
retrieved: 2019-02-14

source: Plk4 is required for cytokinesis and maintenance of chromosomal stability
stated in qid: Q30494556
retrieved: 2019-02-14

source: ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity
stated in qid: Q24322612
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Small GTP-binding proteins and the regulation of the actin cytoskeleton
stated in qid: Q28586463
retrieved: 2019-02-14

source: Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA
stated in qid: Q22253269
retrieved: 2019-02-14

source: Vav GEFs are required for beta2 integrin-dependent functions of neutrophils
stated in qid: Q28590406
retrieved: 2019-02-14

source: Muscle-specific signaling mechanism that links actin dynamics to serum response factor
stated in qid: Q24520637
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis
stated in qid: Q28592451
retrieved: 2019-02-14

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2017-09-16

source: Rho localization in cells and tissues
stated in qid: Q28505019
retrieved: 2019-02-14

source: Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis
stated in qid: Q28510232
retrieved: 2019-02-14

source: The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells
stated in qid: Q28505865
retrieved: 2019-02-14

source: Rho localization in cells and tissues
stated in qid: Q28505019
retrieved: 2017-09-16

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2019-02-14

source: Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase
stated in qid: Q28594420
retrieved: 2019-02-14

wikidata id: Q15331521
domain: protein
level: standard
html url: https://4ort.xyz/entity/ras-homolog-family-member-a-q15331521
markdown url: https://4ort.xyz/entity/ras-homolog-family-member-a-q15331521.md
facts url summary: https://4ort.xyz/entity/ras-homolog-family-member-a-q15331521/facts.json
facts url standard: https://4ort.xyz/entity/ras-homolog-family-member-a-q15331521/facts.json
facts url full: https://4ort.xyz/entity/ras-homolog-family-member-a-q15331521/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-10T01:08:08.254759Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:57:47.609874+00:00Z