# RAP1A, member of RAS oncogene family

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21124363](https://www.wikidata.org/wiki/Q21124363)  
**Source**: https://4ort.xyz/entity/rap1a-member-of-ras-oncogene-family


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P62834)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
5. [Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834)
6. [KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834)
7. [KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
8. [RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
9. [Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
10. [RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
11. [Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
12. [RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
13. [Ras/Rap effector specificity determined by charge reversal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
14. [The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
15. [Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
16. [GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
17. [Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834)
20. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834)
21. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834)
22. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
23. [Ras and Rap control AMPA receptor trafficking during synaptic plasticity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
24. [Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
25. [Rap2A links intestinal cell polarity to brush border formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
26. [Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62834&geneProductId=UniProtKB:P62834)
27. [A ras-related gene with transformation suppressor activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62834)
28. Ensembl Release 99