# Rap guanine nucleotide exchange factor (GEF) 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986717](https://www.wikidata.org/wiki/Q21986717)  
**Source**: https://4ort.xyz/entity/rap-guanine-nucleotide-exchange-factor-gef-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8CHG7)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CHG7)
5. [Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CHG7)
6. [RA-GEF-1 (Rapgef2) is essential for proper development of the midline commissures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CHG7)
7. [The Guanine Nucleotide Exchange Factor CNrasGEF Regulates Melanogenesis and Cell Survival in Melanoma Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CHG7)
8. [Defective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CHG7)
9. [Dorsal telencephalon‐specific RA‐GEF‐1 knockout mice develop heterotopic cortical mass and commissural fiber defect](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CHG7)
10. [Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CHG7)
11. ensembl Release 106