# Rap guanine nucleotide exchange factor 2

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28556909](https://www.wikidata.org/wiki/Q28556909)  
**Source**: https://4ort.xyz/entity/rap-guanine-nucleotide-exchange-factor-2-q28556909


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/F1M386)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F1M386)
5. [nRap GEP: A Novel Neural GDP/GTP Exchange Protein for Rap1 Small G Protein That Interacts with Synaptic Scaffolding Molecule (S-SCAM)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F1M386)
6. [Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F1M386)
7. [Requirement for Plk2 in Orchestrated Ras and Rap Signaling, Homeostatic Structural Plasticity, and Memory](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F1M386)
8. [Direct Binding of the β1 Adrenergic Receptor to the Cyclic AMP-Dependent Guanine Nucleotide Exchange Factor CNrasGEF Leads to Ras Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F1M386)
9. [The guanine nucleotide exchange factor CNrasGEF activates Ras in response to cAMP and cGMP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F1M386)