# Raf-1 proto-oncogene, serine/threonine kinase

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558646](https://www.wikidata.org/wiki/Q28558646)  
**Source**: https://4ort.xyz/entity/raf-1-proto-oncogene-serine-threonine-kinase-q28558646


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P11345)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
6. [Expression of mitogen-activated protein kinase pathways during postnatal development of rat heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
7. [Regulation and role of Raf-1/B-Raf heterodimerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
8. [Hepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
9. [Insulin enhances growth hormone induction of the MEK/ERK signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
10. [Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
11. [Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
12. [RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
13. [Diabetes regulates small molecular weight G-protein, H-Ras, in the microvasculature of the retina: implication in the development of retinopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
14. [beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
15. [Raf kinase activation of adenylyl cyclases: isoform-selective regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
16. [Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
17. [Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11345)
18. ensembl Release 104