# RAD51 recombinase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q3235015](https://www.wikidata.org/wiki/Q3235015)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/RAD51)  
**Source**: https://4ort.xyz/entity/rad51-recombinase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q06609)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06609&geneProductId=UniProtKB:Q06609)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
8. [DNA polymerase POLN participates in cross-link repair and homologous recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
9. [Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
10. [Regulation of Rad51 Function by c-Abl in Response to DNA Damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
11. [RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
12. [A novel nucleic acid-binding protein that interacts with human rad51 recombinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
13. [Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
14. [Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
15. [The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
16. [Inhibition of homologous recombination by the PCNA-interacting protein PARI](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
17. [Highlight: BRCA1 and BRCA2 proteins in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
18. [Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
19. [A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
20. [Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
21. [Regulation and localization of the Bloom syndrome protein in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
22. [The role of the human SWI5-MEI5 complex in homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
23. [Purified human BRCA2 stimulates RAD51-mediated recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
24. [The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
25. [Insights into DNA recombination from the structure of a RAD51-BRCA2 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
26. [XPA versus ERCC1 as chemosensitising agents to cisplatin and mitomycin C in prostate cancer cells: role of ERCC1 in homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
27. [FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
28. [FIGNL1-containing protein complex is required for efficient homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
29. [RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
30. [FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
31. [NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
32. [Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
33. [CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
34. [WRN interacts physically and functionally with the recombination mediator protein RAD52](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
35. [Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
36. [Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
37. [Resistance to therapy caused by intragenic deletion in BRCA2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
38. [Interaction of p53 with the Human Rad51 Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
39. [Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
40. [Interplay between human DNA repair proteins at a unique double-strand break in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
41. [Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
42. [XRCC2 and XRCC3, New Human Rad51-Family Members, Promote Chromosome Stability and Protect against DNA Cross-Links and Other Damages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
43. [Compromised BRCA1-PALB2 interaction is associated with breast cancer risk.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
44. [RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserved motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
45. [ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
46. [The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
47. [hSWS1·SWSAP1 Is an Evolutionarily Conserved Complex Required for Efficient Homologous Recombination Repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
48. [Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
49. [A mitotic function for the high-mobility group protein HMG20b regulated by its interaction with the BRC repeats of the BRCA2 tumor suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)
50. [The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06609)