# RAD50 double strand break repair protein

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105362](https://www.wikidata.org/wiki/Q21105362)  
**Source**: https://4ort.xyz/entity/rad50-double-strand-break-repair-protein


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q92878)
3. Q20641742
4. [ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
5. [The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
7. [ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
8. [Nuclease Activities in a Complex of Human Recombination and DNA Repair Factors Rad50, Mre11, and p95](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
9. [ATRX dysfunction induces replication defects in primary mouse cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
10. [CDK targets Sae2 to control DNA-end resection and homologous recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
11. [MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
12. [Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
13. [RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
15. [Nuclease Activities in a Complex of Human Recombination and DNA Repair Factors Rad50, Mre11, and p95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
16. [ATM-dependent phosphorylation of ATF2 is required for the DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
17. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
18. [A balance between elongation and trimming regulates telomere stability in stem cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
20. [The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
21. [RAD50 and NBS1 form a stable complex functional in DNA binding and tethering](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92878&geneProductId=UniProtKB:Q92878)
22. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
23. [A balance between elongation and trimming regulates telomere stability in stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
24. [The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
25. [RAD50 and NBS1 form a stable complex functional in DNA binding and tethering](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
26. [ATM-dependent phosphorylation of ATF2 is required for the DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
27. [Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
28. [The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
29. [PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
30. [MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
31. [ATM-dependent phosphorylation of nibrin in response to radiation exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
32. [Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92878)
33. ensembl Release 95