# RAD18 E3 ubiquitin protein ligase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135006](https://www.wikidata.org/wiki/Q21135006)  
**Source**: https://4ort.xyz/entity/rad18-e3-ubiquitin-protein-ligase


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
4. [Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
5. [Recognition of forked and single‐stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NS91&geneProductId=UniProtKB:Q9NS91)
7. [Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
8. [The human RAD18 gene product interacts with HHR6A and HHR6B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
10. [A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
11. [Spartan/C1orf124, a Reader of PCNA Ubiquitylation and a Regulator of UV-Induced DNA Damage Response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
12. [Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
13. [RAD18–BRCTx interaction is required for efficient repair of UV-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
14. [A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
15. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
16. [Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
17. [Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
18. [E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
19. [Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
20. [DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
21. [Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NS91&geneProductId=UniProtKB:Q9NS91)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NS91&geneProductId=UniProtKB:Q9NS91)
23. [RAD18–BRCTx interaction is required for efficient repair of UV-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NS91&geneProductId=UniProtKB:Q9NS91)
24. [BRCTx Is a Novel, Highly Conserved RAD18-Interacting Protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NS91&geneProductId=UniProtKB:Q9NS91)
25. [DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NS91&geneProductId=UniProtKB:Q9NS91)
26. [BRCTx Is a Novel, Highly Conserved RAD18-Interacting Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NS91)
27. Ensembl Release 99