# RAD17 checkpoint clamp loader component

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21115925](https://www.wikidata.org/wiki/Q21115925)  
**Source**: https://4ort.xyz/entity/rad17-checkpoint-clamp-loader-component


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O75943)
3. Q20641742
4. [UniProt](http://www.uniprot.org/uniprot/O60671.txt?132)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
6. [Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
7. [The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
8. [Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
9. [Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
10. [HRad17 colocalizes with NHP2L1 in the nucleolus and redistributes after UV irradiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
12. [Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
13. [Identification of a Human Homologue of theSchizosaccharomyces pombe rad17+ Checkpoint Gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
14. [Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75943&geneProductId=UniProtKB:O75943)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75943&geneProductId=UniProtKB:O75943)
16. [MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75943)
17. [Identification of a Human Homologue of theSchizosaccharomyces pombe rad17+ Checkpoint Gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75943&geneProductId=UniProtKB:O75943)
18. Ensembl Release 99