# Rac family small GTPase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q15325768](https://www.wikidata.org/wiki/Q15325768)  
**Source**: https://4ort.xyz/entity/rac-family-small-gtpase-1-q15325768


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63001)
3. Q20641742
4. [The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
5. [The Rho Target PRK2 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
6. [POSH localizes activated Rac1 to control the formation of cytoplasmic dilation of the leading process and neuronal migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
7. [Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
8. [Rho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): a new Ras-related C3 botulinum toxin substrate 1 (Rac1) GTPase-activating protein that controls dendritic spine morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
9. [Oncogene ect2 is related to regulators of small GTP-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
10. [IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
11. [Breast cancer-associated gene 3 (BCA3) is a novel Rac1-interacting protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
12. [Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
13. [The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
14. [Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
15. [Affixin activates Rac1 via betaPIX in C2C12 myoblast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
16. [ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
17. [SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
18. [Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
20. [Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
21. [Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
22. [Vav GEFs are required for beta2 integrin-dependent functions of neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
24. [Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
25. [CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
26. [Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
27. [The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
28. [The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
29. [Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
30. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
31. [Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
32. [Pak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
33. [Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
34. [Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
35. [Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
36. [Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
37. [Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
38. [Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
39. [Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
40. [Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63001&geneProductId=UniProtKB:P63001)
41. [Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
42. [Pak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
43. [Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
44. [Wnt5a regulates midbrain dopaminergic axon growth and guidance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
45. [WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
46. [Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
47. [Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
48. [The small GTPase Rac1 regulates auditory hair cell morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
49. [Rac1 Controls the Subcellular Localization of the Rho Guanine Nucleotide Exchange Factor Net1A To Regulate Focal Adhesion Formation and Cell Spreading](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)
50. [P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63001)