# Pyruvate dehydrogenase E1 subunit alpha 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21118901](https://www.wikidata.org/wiki/Q21118901)  
**Source**: https://4ort.xyz/entity/pyruvate-dehydrogenase-e1-subunit-alpha-1-q21118901


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P08559)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
5. [Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
6. [Structural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
7. [A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
8. [Mutagenesis studies of the phosphorylation sites of recombinant human pyruvate dehydrogenase. Site-specific regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
9. [An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08559&geneProductId=UniProtKB:P08559)
11. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08559&geneProductId=UniProtKB:P08559)
12. [The human pyruvate dehydrogenase complex. Isolation of cDNA clones for the E1 alpha subunit, sequence analysis, and characterization of the mRNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08559&geneProductId=UniProtKB:P08559)
13. [Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08559&geneProductId=UniProtKB:P08559)
14. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
15. [The human pyruvate dehydrogenase complex. Isolation of cDNA clones for the E1 alpha subunit, sequence analysis, and characterization of the mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
17. [Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08559)
18. Ensembl Release 99