Pyrroline-5-carboxylate reductase family, member 2
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
additional property: PropertyValue
  property ID: P361
  value: NAD(P)-binding domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Pyrroline-5-carboxylate reductase
additional property: PropertyValue
  property ID: P527
  value: Pyrroline-5-carboxylate reductase, catalytic, N-terminal
additional property: PropertyValue
  property ID: P527
  value: Pyrroline-5-carboxylate reductase, dimerisation domain
additional property: PropertyValue
  property ID: P637
  value: NP_598466
additional property: PropertyValue
  property ID: P680
  value: oxidoreductase activity
additional property: PropertyValue
  property ID: P680
  value: pyrroline-5-carboxylate reductase activity
additional property: PropertyValue
  property ID: P680
  value: pyrroline-5-carboxylate reductase activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: L-proline biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: cellular amino acid biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: cellular response to oxidative stress
additional property: PropertyValue
  property ID: P702
  value: Pycr2
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000027802
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 7
      unique citations norm: 0.003
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 7
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q922Q4
    source count: 1
    confidence: 0.2
  P361:
    value: Q24780980
    source count: 1
    confidence: 0.2
    value label: 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
  P361:
    value: Q41797412
    source count: 1
    confidence: 0.2
    value label: NAD(P)-binding domain superfamily
  P361:
    value: Q24739281
    source count: 1
    confidence: 0.2
    value label: Pyrroline-5-carboxylate reductase
  P361:
    value: Q83136186
    source count: 1
    confidence: 0.2
    value label: Pyrroline-5-carboxylate reductase, dimerisation domain, protein family
  P361:
    value: Q83166685
    source count: 1
    confidence: 0.2
    value label: Pyrroline-5-carboxylate reductase, catalytic, N-terminal domain, protein family
  P527:
    value: Q24788334
    source count: 1
    confidence: 0.2
    value label: Pyrroline-5-carboxylate reductase, catalytic, N-terminal
  P527:
    value: Q24727477
    source count: 1
    confidence: 0.2
    value label: Pyrroline-5-carboxylate reductase, dimerisation domain
  P637:
    value: NP_598466
    source count: 1
    confidence: 0.2
  P680:
    value: Q14349613
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity
  P680:
    value: Q21119667
    source count: 3
    confidence: 0.6
    value label: pyrroline-5-carboxylate reductase activity
  P680:
    value: Q21119667
    source count: 2
    confidence: 0.4
    value label: pyrroline-5-carboxylate reductase activity
  P680:
    value: Q21119667
    source count: 3
    confidence: 0.6
    value label: pyrroline-5-carboxylate reductase activity
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q39572
    source count: 3
    confidence: 0.6
    value label: mitochondrion
  P682:
    value: Q21105320
    source count: 1
    confidence: 0.2
    value label: L-proline biosynthetic process
  P682:
    value: Q14851773
    source count: 1
    confidence: 0.2
    value label: cellular amino acid biosynthetic process
  P682:
    value: Q14862244
    source count: 2
    confidence: 0.4
    value label: cellular response to oxidative stress
  P682:
    value: Q21097131
    source count: 4
    confidence: 0.8
    value label: proline biosynthetic process
  P682:
    value: Q21105320
    source count: 2
    confidence: 0.4
    value label: L-proline biosynthetic process
  P702:
    value: Q18263495
    source count: 1
    confidence: 0.2
    value label: Pycr2
  P703:
    value: Q83310
    source count: 1
    confidence: 0.2
    value label: house mouse
  P705:
    value: ENSMUSP00000027802
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-05-09

source: GOA
stated in qid: Q28018111
retrieved: 2018-10-11

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-05-09

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21989840
domain: protein
level: standard
html url: https://4ort.xyz/entity/pyrroline-5-carboxylate-reductase-family-member-2
markdown url: https://4ort.xyz/entity/pyrroline-5-carboxylate-reductase-family-member-2.md
facts url summary: https://4ort.xyz/entity/pyrroline-5-carboxylate-reductase-family-member-2/facts.json
facts url standard: https://4ort.xyz/entity/pyrroline-5-carboxylate-reductase-family-member-2/facts.json
facts url full: https://4ort.xyz/entity/pyrroline-5-carboxylate-reductase-family-member-2/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-07T09:42:39.023453Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:25:40.090227+00:00Z