# Pyrroline-5-carboxylate reductase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21119668](https://www.wikidata.org/wiki/Q21119668)  
**Source**: https://4ort.xyz/entity/pyrroline-5-carboxylate-reductase-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P32322)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
5. [Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
6. [DJ-1 cooperates with PYCR1 in cell protection against oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
7. [Cloning human pyrroline-5-carboxylate reductase cDNA by complementation in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32322&geneProductId=UniProtKB:P32322)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32322&geneProductId=UniProtKB:P32322)
9. [Crystal structure of human pyrroline-5-carboxylate reductase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32322&geneProductId=UniProtKB:P32322)
10. [DJ-1 cooperates with PYCR1 in cell protection against oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32322&geneProductId=UniProtKB:P32322)
11. [Functional specialization in proline biosynthesis of melanoma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32322&geneProductId=UniProtKB:P32322)
12. [Purified human erythrocyte pyrroline-5-carboxylate reductase. Preferential oxidation of NADPH](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
13. [Crystal structure of human pyrroline-5-carboxylate reductase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
14. [Cloning human pyrroline-5-carboxylate reductase cDNA by complementation in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
16. [Mutations in PYCR1 cause cutis laxa with progeroid features](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32322)
17. Ensembl Release 99