# PTEN induced putative kinase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986264](https://www.wikidata.org/wiki/Q21986264)  
**Source**: https://4ort.xyz/entity/pten-induced-putative-kinase-1


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
4. [BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MQ3&geneProductId=UniProtKB:Q99MQ3)
6. [Ubiquitin is phosphorylated by PINK1 to activate parkin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MQ3&geneProductId=UniProtKB:Q99MQ3)
7. [PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MQ3&geneProductId=UniProtKB:Q99MQ3)
8. [BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MQ3&geneProductId=UniProtKB:Q99MQ3)
9. [PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MQ3&geneProductId=UniProtKB:Q99MQ3)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
11. [Ubiquitin is phosphorylated by PINK1 to activate parkin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
12. [PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
13. [PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
14. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MQ3&geneProductId=UniProtKB:Q99MQ3)
15. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
16. [PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
17. [Inactivation of Pink1 Gene in Vivo Sensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes, Parkin or DJ-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
18. [Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
19. [Loss of PINK1 attenuates HIF-1α induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
20. [Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
21. [Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
22. [BAG5 Protects against Mitochondrial Oxidative Damage through Regulating PINK1 Degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MQ3&geneProductId=UniProtKB:Q99MQ3)
23. [BAG5 Protects against Mitochondrial Oxidative Damage through Regulating PINK1 Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MQ3)
24. ensembl Release 106