# Protocadherin 15

> mammalian protein found in Mus musculus

**Wikidata**: [Q21989859](https://www.wikidata.org/wiki/Q21989859)  
**Source**: https://4ort.xyz/entity/protocadherin-15


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99PJ1)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
5. [Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
6. [The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
7. [Interactions in the network of Usher syndrome type 1 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
8. [TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
9. [Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
10. [Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
11. [Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
12. [Photoreceptor expression of the Usher syndrome type 1 protein protocadherin 15 (USH1F) and its interaction with the scaffold protein harmonin (USH1C)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
13. [Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
14. [A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
15. [Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
16. [Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99PJ1&geneProductId=UniProtKB:Q99PJ1)
17. [The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
18. [PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99PJ1&geneProductId=UniProtKB:Q99PJ1)
20. [PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99PJ1&geneProductId=UniProtKB:Q99PJ1)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
22. [Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
23. [A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
24. [Characterization of a new allele of Ames waltzer generated by ENU mutagenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
25. [Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
26. [Neuroepithelial defects of the inner ear in a new allele of the mouse mutation Ames waltzer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
27. [A new mouse insertional mutation that causes sensorineural deafness and vestibular defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
28. [Severe vestibular and auditory impairment in three alleles of Ames waltzer (av) mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
29. [Electron Microscopic Studies of Capillary Permeability in Normal and Ames Waltzer Deaf Mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
30. [Fine genetic and comparative mapping of the deafness mutation Ames waltzer on mouse chromosome 10](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
31. [Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
32. [A new spontaneous mutation in the mouse protocadherin 15 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
33. [Ames Waltzer deaf mice have reduced electroretinogram amplitudes and complex alternative splicing of Pcdh15 transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PJ1)
34. ensembl Release 106