# Protein phosphatase 3 catalytic subunit alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21132155](https://www.wikidata.org/wiki/Q21132155)  
**Source**: https://4ort.xyz/entity/protein-phosphatase-3-catalytic-subunit-alpha


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q08209)
3. Q20641742
4. [Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
6. [Genetic conservation of the immunophilin-binding domains of human calcineurin A1 and A2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
7. [Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
9. [The complex structure of calmodulin bound to a calcineurin peptide](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
10. [Genetic conservation of the immunophilin-binding domains of human calcineurin A1 and A2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
11. [Domain Swapping and Different Oligomeric States for the Complex Between Calmodulin and the Calmodulin-Binding Domain of Calcineurin A](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
12. [Investigating the human Calcineurin Interaction Network using the πɸLxVP SLiM.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
13. [Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
14. [Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
15. [NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
16. [Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
17. [Calsarcins, a novel family of sarcomeric calcineurin-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
18. [Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
19. [Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
20. [Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
21. [Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
22. [A directed protein interaction network for investigating intracellular signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
23. [Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
24. [A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
25. [WITHDRAWN: USP14 stabilizes calcineurin and regulates NFAT/AP-1 dependent IL-4 transcription as a novel calcineurin-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
26. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
27. [Direct association of the unique C‐terminal tail of transmembrane AMPA receptor regulatory protein γ‐8 with calcineurin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
28. [Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
29. [Na+/H+ Exchanger 1 Directly Binds to Calcineurin A and Activates Downstream NFAT Signaling, Leading to Cardiomyocyte Hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
30. [Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
31. [CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
32. [The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
33. [The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
34. [The complex structure of calmodulin bound to a calcineurin peptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
35. [Domain Swapping and Different Oligomeric States for the Complex Between Calmodulin and the Calmodulin-Binding Domain of Calcineurin A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
36. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
37. [Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
38. [The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
39. [The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
40. [CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
41. [Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
42. [Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
43. [Investigating the human Calcineurin Interaction Network using the πɸLxVP SLiM.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
44. [Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
45. [Na+/H+ Exchanger 1 Directly Binds to Calcineurin A and Activates Downstream NFAT Signaling, Leading to Cardiomyocyte Hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
46. [Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
47. [Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08209&geneProductId=UniProtKB:Q08209)
48. [The effect of down regulation of calcineurin Aα by lentiviral vector-mediated RNAi on the biological behavior of small-cell lung cancer and its bone metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
49. [Calcineurin promotes proliferation, migration, and invasion of small cell lung cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)
50. [Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08209)