# Protein phosphatase 3, catalytic subunit, alpha isoform

> mammalian protein found in Mus musculus

**Wikidata**: [Q21980094](https://www.wikidata.org/wiki/Q21980094)  
**Source**: https://4ort.xyz/entity/protein-phosphatase-3-catalytic-subunit-alpha-isoform


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63328)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
5. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63328)
6. [Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
7. [Cooperative autoinhibition and multi-level activation mechanisms of calcineurin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
8. [PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
9. [Calcium-dependent interaction of calcineurin with Bcl-2 in neuronal tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
10. [Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
11. [KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
12. [Interaction of calcineurin and type-A GABA receptor gamma 2 subunits produces long-term depression at CA1 inhibitory synapses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
13. [Tau binds both subunits of calcineurin, and binding is impaired by calmodulin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
14. [Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
15. [Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
16. [CIB1 is a regulator of pathological cardiac hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
17. [Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63328)
18. [Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63328&geneProductId=UniProtKB:P63328)
21. [Calcium-dependent interaction of calcineurin with Bcl-2 in neuronal tissue](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63328&geneProductId=UniProtKB:P63328)
22. [Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63328&geneProductId=UniProtKB:P63328)
23. [Inducible and reversible enhancement of learning, memory, and long-term potentiation by genetic inhibition of calcineurin.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
24. [Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
25. [Temporal regulation of nuclear factor one occupancy by calcineurin/NFAT governs a voltage-sensitive developmental switch in late maturing neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
26. [Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63328)
27. [KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63328)
28. [Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63328)
29. [Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63328)
30. [MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63328)
31. [Regulation of MEF2 transcriptional activity by calcineurin/mAKAP complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
32. [Retina-driven dephosphorylation of the NR2A subunit correlates with faster NMDA receptor kinetics at developing retinocollicular synapses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
33. [Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
34. [Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
35. [Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
36. [Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
37. [Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
38. [Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
39. [Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
40. [Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
41. [Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
42. [MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
43. [Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
44. [Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
45. [The transcription factor NF-ATc is essential for cardiac valve formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
46. [Calcineurin-dependent nuclear translocation of a murine transcription factor NFATx: molecular cloning and functional characterization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63328)
47. ensembl Release 106