# Protein phosphatase 2 scaffold subunit Aalpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114977](https://www.wikidata.org/wiki/Q21114977)  
**Source**: https://4ort.xyz/entity/protein-phosphatase-2-scaffold-subunit-aalpha


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P30153)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30153&geneProductId=UniProtKB:P30153)
5. [PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
6. [Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
7. [A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
8. [Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
9. [FAM122A, a new endogenous inhibitor of protein phosphatase 2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
10. [Binding specificity of protein phosphatase 2A core enzyme for regulatory B subunits and T antigens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
11. [A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
12. [Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
13. [Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
14. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
15. [An integrated workflow for charting the human interaction proteome: insights into the PP2A system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
16. [The tumor suppressor PP2A Abeta regulates the RalA GTPase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
17. [Structural mechanism of demethylation and inactivation of protein phosphatase 2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
18. [CIP2A inhibits PP2A in human malignancies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
19. [ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
20. [PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
21. [Mechanisms of the HRSL3 tumor suppressor function in ovarian carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
22. [Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
23. [Protein phosphatase 2A interacts with and directly dephosphorylates RelA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
24. [An organelle-specific protein landscape identifies novel diseases and molecular mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
25. [PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
26. [Identification of structural elements involved in the interaction of simian virus 40 small tumor antigen with protein phosphatase 2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
27. [AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
28. [Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: evidence for a heterotrimeric form of protein phosphatase 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
29. [B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
30. [Single-step Strep-tag purification for the isolation and identification of protein complexes from mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
31. [Methylation of the C-terminal leucine residue of the PP2A catalytic subunit is unnecessary for the catalytic activity and the binding of regulatory subunit (PR55/B).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
32. [Interaction of nucleoredoxin with protein phosphatase 2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
33. [An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
34. [Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
35. [Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
36. [Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
37. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
38. [The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
39. [Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
40. [Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
41. [Type 2A protein phosphatase, the complex regulator of numerous signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30153&geneProductId=UniProtKB:P30153)
42. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
43. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
44. [Type 2A protein phosphatase, the complex regulator of numerous signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
45. [Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30153&geneProductId=UniProtKB:P30153)
46. [Structure of the protein phosphatase 2A holoenzyme](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30153&geneProductId=UniProtKB:P30153)
47. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30153&geneProductId=UniProtKB:P30153)
48. [Structure of the protein phosphatase 2A holoenzyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
49. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)
50. [Absence of PPP2R1A mutations in Wilms tumor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30153)