# Protein kinase MEC1 YBR136W

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27548640](https://www.wikidata.org/wiki/Q27548640)  
**Source**: https://4ort.xyz/entity/protein-kinase-mec1-ybr136w


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P38111)
3. Q20641742
4. [Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
5. [Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38111&geneProductId=UniProtKB:P38111)
8. [Dpb11 coordinates Mec1 kinase activation with cell cycle‐regulated Rad9 recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
9. [LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
10. [3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
11. [A Global Protein Kinase and Phosphatase Interaction Network in Yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
12. [Uncoupling of Unwinding from DNA Synthesis Implies Regulation of MCM Helicase by Tof1/Mrc1/Csm3 Checkpoint Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
13. [The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
14. [Dpb11 activates the Mec1–Ddc2 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
16. [The C-terminal Residues ofSaccharomyces cerevisiaeMec1 Are Required for Its Localization, Stability, and Function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38111&geneProductId=UniProtKB:P38111)
17. [The C-terminal Residues ofSaccharomyces cerevisiaeMec1 Are Required for Its Localization, Stability, and Function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
18. [Toward the Complete Yeast Mitochondrial Proteome: Multidimensional Separation Techniques for Mitochondrial Proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
19. [The proteome of Saccharomyces cerevisiae mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
20. [Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
21. [Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
22. [Mec1/Tel1 Phosphorylation of the INO80 Chromatin Remodeling Complex Influences DNA Damage Checkpoint Responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
23. [Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
24. [A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
25. [ATR-like kinase Mec1 facilitates both chromatin accessibility at DNA replication forks and replication fork progression during replication stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
26. [Late S Phase-Specific Recruitment of Mre11 Complex Triggers Hierarchical Assembly of Telomere Replication Proteins in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=P38111&geneProductId=UniProtKB:P38111)
27. [Late S Phase-Specific Recruitment of Mre11 Complex Triggers Hierarchical Assembly of Telomere Replication Proteins in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38111)
28. ensembl Release 106