# Protein kinase D2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21113377](https://www.wikidata.org/wiki/Q21113377)  
**Source**: https://4ort.xyz/entity/protein-kinase-d2-q21113377


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9BZL6)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
5. [Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
6. [PKD2 interacts with Lck and regulates NFAT activity in T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
7. [Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZL6&geneProductId=UniProtKB:Q9BZL6)
9. [Molecular Cloning and Characterization of the Human Protein Kinase D2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZL6&geneProductId=UniProtKB:Q9BZL6)
10. [Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZL6&geneProductId=UniProtKB:Q9BZL6)
11. [Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZL6&geneProductId=UniProtKB:Q9BZL6)
12. [Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
13. [Molecular Cloning and Characterization of the Human Protein Kinase D2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
14. [Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
15. [Identification of Protein Kinase D2 as a Pivotal Regulator of Endothelial Cell Proliferation, Migration, and Angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
16. [The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
17. [Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
18. [Protein kinase D in vascular biology and angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
19. [Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BZL6&geneProductId=UniProtKB:Q9BZL6)
20. [Protein Kinase D Regulates RhoA Activity via Rhotekin Phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
21. [Protein Kinase D2 Mediates Activation of Nuclear Factor κB by Bcr-Abl in Bcr-Abl+ Human Myeloid Leukemia Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
22. [Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-κB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
23. [Angiotensin II Directly Triggers Endothelial Exocytosis via Protein Kinase C-Dependent Protein Kinase D2 Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BZL6)
25. Ensembl Release 99
26. UMLS 2023