# Protein kinase D1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116913](https://www.wikidata.org/wiki/Q21116913)  
**Source**: https://4ort.xyz/entity/protein-kinase-d1-q21116913


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL565612)
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL494089)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q15139)
5. Q20641742
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
7. [Tyrosine Phosphorylation of Protein Kinase D in the Pleckstrin Homology Domain Leads to Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
8. [A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
9. [Centaurin-α1 associates with and is phosphorylated by isoforms of protein kinase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
10. [PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
11. [Protein Kinase C μ Is Regulated by the Multifunctional Chaperon Protein p32](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
12. [E-cadherin phosphorylation by protein kinase D1/protein kinase C{mu} is associated with altered cellular aggregation and motility in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
13. [Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
14. [Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
15. [Metallothionein 2A interacts with the kinase domain of PKCμ in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
16. [Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
17. [PKCu is a novel, atypical member of the protein kinase C family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
18. [Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
19. [Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
20. [Protein Kinase D Regulates the Fission of Cell Surface Destined Transport Carriers from the Trans-Golgi Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
21. [Spatial and temporal regulation of protein kinase D (PKD)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
22. [PKCu is a novel, atypical member of the protein kinase C family](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15139&geneProductId=UniProtKB:Q15139)
23. [Protein Kinase D Controls the Integrity of Golgi Apparatus and the Maintenance of Dendritic Arborization in Hippocampal Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
24. [Protein kinase D in vascular biology and angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
25. [The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
26. [Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
27. [Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15139&geneProductId=UniProtKB:Q15139)
28. [Protein kinase D mediates a stress‐induced NF‐κB activation and survival pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
29. [Protein Kinase D-dependent Phosphorylation and Nuclear Export of Histone Deacetylase 5 Mediates Vascular Endothelial Growth Factor-induced Gene Expression and Angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
30. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15139)
31. Ensembl Release 99