# Protein kinase cAMP-dependent type II regulatory subunit alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105026](https://www.wikidata.org/wiki/Q21105026)  
**Source**: https://4ort.xyz/entity/protein-kinase-camp-dependent-type-ii-regulatory-subunit-alpha-q21105026


## References

1. UniProt
2. [BioGRID](https://thebiogrid.org/news/227)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P13861)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
6. [Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
7. [The testis-specific Cα2 subunit of PKA is kinetically indistinguishable from the common Cα1 subunit of PKA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
8. [Characterization of an A-kinase anchoring protein in human ciliary axonemes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
9. [A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
10. [Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
11. [GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis signaling in the regulation of mitochondrial elongation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
12. [The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
13. [Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
14. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
15. [Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
16. [An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
17. [Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
18. [Differential PKA activation and AKAP association determines cell fate in cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
19. [Binding of PKA-RIIalpha to the Adenovirus E1A12S oncoprotein correlates with its nuclear translocation and an increase in PKA-dependent promoter activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
20. [Molecular cloning, upstream sequence and promoter studies of the human gene for the regulatory subunit RII alpha of cAMP-dependent protein kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
21. [Control of PKA stability and signalling by the RING ligase praja2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
22. [A systematic evaluation of protein kinase A-A-kinase anchoring protein interaction motifs.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
24. [Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
25. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13861&geneProductId=UniProtKB:P13861)
26. [Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
27. [Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13861&geneProductId=UniProtKB:P13861)
28. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13861&geneProductId=UniProtKB:P13861)
29. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13861&geneProductId=UniProtKB:P13861)
30. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13861&geneProductId=UniProtKB:P13861)
31. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13861&geneProductId=UniProtKB:P13861)
32. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13861&geneProductId=UniProtKB:P13861)
33. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
34. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
35. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
36. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
37. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
38. [Human testis cDNA for the regulatory subunit RII alpha of cAMP-dependent protein kinase encodes an alternate amino-terminal region](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13861)
39. Ensembl Release 99