# protein kinase C zeta

> mammalian protein found in Homo sapiens

**Wikidata**: [Q906403](https://www.wikidata.org/wiki/Q906403)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Protein_kinase_C_zeta_type)  
**Source**: https://4ort.xyz/entity/protein-kinase-c-zeta


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q05513)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513)
7. [Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
8. [Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513)
9. [Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513)
10. [Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
11. [A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
12. [Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
13. [Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
14. [APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
15. [WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
16. [p62 forms a ternary complex with PKCζ and PAR‐4 and antagonizes PAR‐4‐induced PKCζ inhibition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
17. [KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
18. [A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
19. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
20. [Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
21. [TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
22. [PKCtheta cooperates with atypical PKCzeta and PKCiota in NF-kappaB transactivation of T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
23. [Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
24. [Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
25. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
26. [Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein-protein interactions in relation to subcellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
27. [Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
28. [PKCzetaII is a target for degradation through the tumour suppressor protein pVHL](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
29. [Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
30. [Novel PKC-ζ to p47phox interaction is necessary for transformation from blebbishields](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
31. [mTORC2 phosphorylates protein kinase Cζ to regulate its stability and activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
32. [Pooled-matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
33. [Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
34. [aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
35. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
36. [Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
37. [Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
38. [Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513)
39. [CCM1 regulates vascular-lumen organization by inducing endothelial polarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
40. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513)
41. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
42. [Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
43. [The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
44. [The cDNA sequence encoding human protein kinase C-zeta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513)
45. Ensembl Release 99