# Proteasome 20S subunit alpha 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111454](https://www.wikidata.org/wiki/Q21111454)  
**Source**: https://4ort.xyz/entity/proteasome-20s-subunit-alpha-3


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL451887)
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2141296)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2103884)
5. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P25788)
6. Q20641742
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
9. [A human protein-protein interaction network: a resource for annotating the proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
10. [A directed protein interaction network for investigating intracellular signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
11. [Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
12. [Mapping and structural dissection of human 20 S proteasome using proteomic approaches](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
13. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
14. [The alpha4 and alpha7 subunits and assembly of the 20S proteasome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
15. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
16. [Mutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
17. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
18. [The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
19. [An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
20. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
21. [Protein-protein interactions among human 20S proteasome subunits and proteassemblin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
22. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
23. [The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
24. [The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
25. [The transcriptional repressor protein PRH interacts with the proteasome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
27. [BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
28. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
29. [Structure and functions of the 20S and 26S proteasomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
30. [Mass spectrometric characterization of the affinity-purified human 26S proteasome complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
31. [Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
32. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
33. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
34. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
35. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
36. [The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
37. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
38. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
39. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
40. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25788)
41. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25788&geneProductId=UniProtKB:P25788)
42. Ensembl Release 99
43. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)