# Prospero homeobox 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114237](https://www.wikidata.org/wiki/Q21114237)  
**Source**: https://4ort.xyz/entity/prospero-homeobox-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q92786)
3. Q20641742
4. [Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
6. [Prospero-related homeobox protein (Prox1) inhibits hepatitis B virus replication through repressing multiple cis regulatory elements](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
7. [Functional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologue](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
8. [Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
9. [A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
10. [Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
11. [COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
12. [Functional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
15. [A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
16. [Prospero-related homeobox protein (Prox1) inhibits hepatitis B virus replication through repressing multiple cis regulatory elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
17. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
18. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
19. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
20. [Prox1 is differentially localized during lens development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
21. [COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
22. [Prox1 is differentially localized during lens development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
24. [Prox1 is a marker of ectodermal placodes, endodermal compartments, lymphatic endothelium and lymphangioblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
25. [Structure and chromosomal localization of the human homeobox gene Prox 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
26. [Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
27. [Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92786&geneProductId=UniProtKB:Q92786)
28. [The homeobox transcription factor Prox1 is highly conserved in embryonic hepatoblasts and in adult and transformed hepatocytes, but is absent from bile duct epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
29. [Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
30. [Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
31. [Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
32. [A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
33. [Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92786)
34. Ensembl Release 99