# Prospero homeobox 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21990473](https://www.wikidata.org/wiki/Q21990473)  
**Source**: https://4ort.xyz/entity/prospero-homeobox-1-q21990473


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P48437)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
5. [Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
7. [Prox1 maintains muscle structure and growth in the developing heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
9. [Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors - and -mediated transactivation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
10. [Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors - and -mediated transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
11. [Prox1 maintains muscle structure and growth in the developing heart](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
12. [Prox1 Promotes Lineage-specific Expression of Fibroblast Growth Factor (FGF) Receptor-3 in Lymphatic Endothelium: A Role for FGF Signaling in Lymphangiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
13. [Prox1 is differentially localized during lens development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
14. [PCNA interacts with Prox1 and represses its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
15. [Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
16. [Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
17. [Prox1 is differentially localized during lens development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
18. [Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
19. [PCNA interacts with Prox1 and represses its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
21. [Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
22. [Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
23. [The homeobox transcription factor Prox1 is highly conserved in embryonic hepatoblasts and in adult and transformed hepatocytes, but is absent from bile duct epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
24. [Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
25. [Hepatocyte migration during liver development requires Prox1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
26. [Pancreas-Specific Deletion of Prox1 Affects Development and Disrupts Homeostasis of the Exocrine Pancreas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
27. [Prox1 function is crucial for mouse lens-fibre elongation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
28. [Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
29. [An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
30. [Canal Cristae Growth and Fiber Extension to the Outer Hair Cells of the Mouse Ear Require Prox1 Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
31. [Prox1 Promotes Lineage-specific Expression of Fibroblast Growth Factor (FGF) Receptor-3 in Lymphatic Endothelium: A Role for FGF Signaling in Lymphangiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
32. [Prox1 function is crucial for mouse lens-fibre elongation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437)
33. [Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437)
34. ensembl Release 106