# Proprotein convertase subtilisin/kexin type 9

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986639](https://www.wikidata.org/wiki/Q21986639)  
**Source**: https://4ort.xyz/entity/proprotein-convertase-subtilisin-kexin-type-9-q21986639


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q80W65)
3. Q20641742
4. [Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
6. [Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
7. [The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80W65&geneProductId=UniProtKB:Q80W65)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80W65&geneProductId=UniProtKB:Q80W65)
9. [The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
11. [SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
12. [Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80W65&geneProductId=UniProtKB:Q80W65)
13. [Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80W65&geneProductId=UniProtKB:Q80W65)
14. [Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
15. [Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
16. [Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
17. [Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
18. [PCSK9 regulates neuronal apoptosis by adjusting ApoER2 levels and signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
19. [Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
20. [Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80W65&geneProductId=UniProtKB:Q80W65)
21. [Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80W65)
22. ensembl Release 106