# Proprotein convertase subtilisin/kexin type 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7250440](https://www.wikidata.org/wiki/Q7250440)  
**Source**: https://4ort.xyz/entity/proprotein-convertase-subtilisin-kexin-type-2-q7250440


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P16519)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519)
5. [7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519)
7. [Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519)
8. [Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519)
10. [Calcium- and pH-dependent aggregation and membrane association of the precursor of the prohormone convertase PC2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519)
11. [Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519)
12. [Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16519&geneProductId=UniProtKB:P16519)
13. [Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519)
14. [Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519)
15. [Calcium- and pH-dependent aggregation and membrane association of the precursor of the prohormone convertase PC2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16519)
16. Ensembl Release 99
17. UMLS 2023