prolactin receptor
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P16471
additional property: PropertyValue
  property ID: P361
  value: Fibronectin type III superfamily
additional property: PropertyValue
  property ID: P361
  value: PRLR
additional property: PropertyValue
  property ID: P361
  value: Immunoglobulin-like fold
additional property: PropertyValue
  property ID: P486
  value: D011981
additional property: PropertyValue
  property ID: P527
  value: Long hematopoietin receptor, single chain, conserved site
additional property: PropertyValue
  property ID: P527
  value: fibronectin type III
additional property: PropertyValue
  property ID: P527
  value: Growth hormone/erythropoietin receptor, ligand binding
additional property: PropertyValue
  property ID: P637
  value: NP_000940
additional property: PropertyValue
  property ID: P637
  value: NP_001191243
additional property: PropertyValue
  property ID: P637
  value: NP_001191244
additional property: PropertyValue
  property ID: P638
  value: 2LFG
additional property: PropertyValue
  property ID: P638
  value: 3NCF
additional property: PropertyValue
  property ID: P638
  value: 3N0P
additional property: PropertyValue
  property ID: P672
  value: D12.776.543.750.720.600.710
additional property: PropertyValue
  property ID: P672
  value: D12.776.543.750.750.555.710
additional property: PropertyValue
  property ID: P672
  value: D12.776.543.750.750.660.350.725
additional property: PropertyValue
  property ID: P680
  value: ornithine decarboxylase activator activity
additional property: PropertyValue
  property ID: P680
  value: protein homodimerization activity
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P682
  value: growth hormone receptor signaling pathway via JAK-STAT
additional property: PropertyValue
  property ID: P682
  value: negative regulation of apoptotic process
additional property: PropertyValue
  property ID: P682
  value: cell surface receptor signaling pathway
additional property: PropertyValue
  property ID: P702
  value: PRLR
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000231423
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 18
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 18
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P16471
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797245
    source count: 1
    confidence: 0.2
    value label: Fibronectin type III superfamily
  P361:
    value: Q2738985
    source count: 1
    confidence: 0.2
    value label: PRLR
  P361:
    value: Q24787648
    source count: 1
    confidence: 0.2
    value label: Immunoglobulin-like fold
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83137093
    source count: 1
    confidence: 0.2
    value label: Fibronectin type III, protein family
  P486:
    value: D011981
    source count: 0
    confidence: 0.0
  P527:
    value: Q24740197
    source count: 1
    confidence: 0.2
    value label: Long hematopoietin receptor, single chain, conserved site
  P527:
    value: Q24740327
    source count: 1
    confidence: 0.2
    value label: fibronectin type III
  P527:
    value: Q24785206
    source count: 1
    confidence: 0.2
    value label: Growth hormone/erythropoietin receptor, ligand binding
  P637:
    value: NP_000940
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001191243
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001191244
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001191245
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001191246
    source count: 1
    confidence: 0.2
  P638:
    value: 2LFG
    source count: 1
    confidence: 0.2
  P638:
    value: 3NCF
    source count: 1
    confidence: 0.2
  P638:
    value: 3N0P
    source count: 1
    confidence: 0.2
  P638:
    value: 3NCC
    source count: 1
    confidence: 0.2
  P638:
    value: 3N06
    source count: 1
    confidence: 0.2

value: D12.776.543.750.720.600.710
source count: 0
confidence: 0.0

value: D12.776.543.750.750.555.710
source count: 0
confidence: 0.0

value: D12.776.543.750.750.660.350.725
source count: 0
confidence: 0.0

value: Q21173523
source count: 1
confidence: 0.2
value label: ornithine decarboxylase activator activity

value: Q14762996
source count: 1
confidence: 0.2
value label: protein homodimerization activity

value: Q13667380
source count: 1
confidence: 0.2
value label: metal ion binding

value: Q14875276
source count: 1
confidence: 0.2
value label: peptide hormone binding

value: Q167149
source count: 1
confidence: 0.2
value label: protein binding

value: Q14327652
source count: 1
confidence: 0.2
value label: integral component of membrane

value: Q14349455
source count: 2
confidence: 0.4
value label: membrane

value: Q29548
source count: 1
confidence: 0.2
value label: plasma membrane

value: Q14758890
source count: 1
confidence: 0.2
value label: endosome lumen

value: Q14645596
source count: 1
confidence: 0.2
value label: extracellular region

value: Q14820585
source count: 1
confidence: 0.2
value label: growth hormone receptor signaling pathway via JAK-STAT

value: Q14599533
source count: 1
confidence: 0.2
value label: negative regulation of apoptotic process

value: Q14820580
source count: 1
confidence: 0.2
value label: cell surface receptor signaling pathway

value: Q14864682
source count: 1
confidence: 0.2
value label: activation of transmembrane receptor protein tyrosine kinase activity

value: Q21154920
source count: 1
confidence: 0.2
value label: prolactin signaling pathway

value: Q2738985
source count: 1
confidence: 0.2
value label: PRLR

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000231423
source count: 1
confidence: 0.2

value: ENSP00000309008
source count: 1
confidence: 0.2

value: ENSP00000311613
source count: 1
confidence: 0.2

value: ENSP00000425300
source count: 1
confidence: 0.2

value: ENSP00000422556
source count: 1
confidence: 0.2

value: http://purl.uniprot.org/uniprot/P16471
source count: 1
confidence: 0.2

value: C0034834
source count: 1
confidence: 0.2

source: Functional characterization of the intermediate isoform of the human prolactin receptor
stated in qid: Q22010878
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: The X-ray structure of a growth hormone-prolactin receptor complex
stated in qid: Q24309612
retrieved: 2018-03-27

source: Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins
stated in qid: Q24306111
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-03-27

source: Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells
stated in qid: Q28118923
retrieved: 2018-03-27

source: Functional characterization of the intermediate isoform of the human prolactin receptor
stated in qid: Q22010878
retrieved: 2018-03-27

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells
stated in qid: Q28118923
retrieved: 2019-04-08

source: The X-ray structure of a growth hormone-prolactin receptor complex
stated in qid: Q24309612
retrieved: 2019-04-08

source: Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse
stated in qid: Q24315716
retrieved: 2019-04-08

source: Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2
stated in qid: Q27302085
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: UMLS 2023
stated in qid: Q118645236
retrieved: 2023-05-24

source: Ensembl Release 99
stated in qid: Q83867711

source: Identifiers.org
stated in qid: Q16335166

wikidata id: Q22675913
domain: protein
level: standard
html url: https://4ort.xyz/entity/prolactin-receptor
markdown url: https://4ort.xyz/entity/prolactin-receptor.md
facts url summary: https://4ort.xyz/entity/prolactin-receptor/facts.json
facts url standard: https://4ort.xyz/entity/prolactin-receptor/facts.json
facts url full: https://4ort.xyz/entity/prolactin-receptor/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T03:46:23.171103Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:59:07.553799+00:00Z