# Programmed cell death 6 interacting protein

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114029](https://www.wikidata.org/wiki/Q21114029)  
**Source**: https://4ort.xyz/entity/programmed-cell-death-6-interacting-protein-q21114029


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8WUM4)
3. Q20641742
4. [The Protein Network of HIV Budding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
5. [Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
6. [The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
7. [ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
8. [Structural Analysis of the Complex between Penta-EF-Hand ALG-2 Protein and Sec31A Peptide Reveals a Novel Target Recognition Mechanism of ALG-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
9. [Syndecan-syntenin-ALIX regulates the biogenesis of exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
10. [Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
11. [The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
12. [Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
13. [A physical interaction network of dengue virus and human proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
14. [Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
15. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
16. [Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
17. [ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
18. [Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
19. [ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
20. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
21. [Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
22. [Protein interactions of the transcription factor Hoxa1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
23. [Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
24. [Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
25. [TEX14 Interacts with CEP55 To Block Cell Abscission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
26. [The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
27. [ALIX-CHMP4 interactions in the human ESCRT pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
28. [Structural basis for Ca2+ -dependent formation of ALG-2/Alix peptide complex: Ca2+/EF3-driven arginine switch mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
29. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
30. [Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
31. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
32. [ALIX binds a YPX3L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
33. [VPS37 Isoforms Differentially Modulate the Ternary Complex Formation of ALIX, ALG-2, and ESCRT-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
34. [Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
35. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
36. [Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
37. [The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
38. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
39. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
40. [Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
41. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
42. [Identification and proteomic profiling of exosomes in human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
43. [Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
44. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
45. [Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
46. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
47. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WUM4&geneProductId=UniProtKB:Q8WUM4)
48. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
49. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)
50. [Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WUM4)