# Programmed cell death 4

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21101882](https://www.wikidata.org/wiki/Q21101882)  
**Source**: https://4ort.xyz/entity/programmed-cell-death-4-q21101882


## References

1. UniProt
2. Q20641742
3. [Akt phosphorylates and regulates Pdcd4 tumor suppressor protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
4. [Up-regulation of PDCD4 in senescent human diploid fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
5. [Tumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
6. [PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
7. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
8. [Crystal structure of the eIF4A-PDCD4 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
9. [Interactome mapping suggests new mechanistic details underlying Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53EL6&geneProductId=UniProtKB:Q53EL6)
12. [Akt phosphorylates and regulates Pdcd4 tumor suppressor protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53EL6&geneProductId=UniProtKB:Q53EL6)
13. [Up-regulation of PDCD4 in senescent human diploid fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53EL6&geneProductId=UniProtKB:Q53EL6)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
15. [Micro-RNA-21 regulates TGF-β-induced myofibroblast differentiation by targeting PDCD4 in tumor-stroma interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
16. [Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
17. [Endothelial apoptosis in pulmonary hypertension is controlled by a microRNA/programmed cell death 4/caspase-3 axis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
18. [SMAD proteins control DROSHA-mediated microRNA maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
19. [Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
20. [Peroxisome proliferator-activated receptor-γ enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53EL6)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5VZS7)
22. Ensembl Release 99
23. UMLS 2023