# Prion protein

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28556940](https://www.wikidata.org/wiki/Q28556940)  
**Source**: https://4ort.xyz/entity/prion-protein


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P13852)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
6. [Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
7. [Cellular prion protein localizes to the nucleus of endocrine and neuronal cells and interacts with structural chromatin components](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
8. [Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
9. [Rdj2, a J protein family member, interacts with cellular prion PrP(C)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
10. [Interaction between the cellular prion (PrPC) and the 2P domain K+ channel TREK-1 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
11. [Pronounced cytosolic aggregation of cellular prion protein in pancreatic beta-cells in response to hyperglycemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
12. [The membrane environment of endogenous cellular prion protein in primary rat cerebellar neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
13. [Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
14. [The interaction between prion protein and laminin modulates memory consolidation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
15. [Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
16. [Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
17. [Induction of cellular prion protein gene expression by copper in neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
18. [Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13852)
19. ensembl Release 104