# presenilin enhancer, gamma-secretase subunit

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21130783](https://www.wikidata.org/wiki/Q21130783)  
**Source**: https://4ort.xyz/entity/presenilin-enhancer-gamma-secretase-subunit-q21130783


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1090771)
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL463981)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1770916)
5. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9NZ42)
6. Q20641742
7. [TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
8. [Ferritin light chain interacts with PEN-2 and affects γ-secretase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
9. [Cellular localization of Nicastrin affects amyloid beta species production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
11. [Purification and characterization of the human gamma-secretase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
12. [Three-dimensional structure of human γ-secretase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
13. [An atomic structure of human γ-secretase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
14. [An atomic structure of human γ-secretase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ42&geneProductId=UniProtKB:Q9NZ42)
15. [Three-dimensional structure of human γ-secretase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ42&geneProductId=UniProtKB:Q9NZ42)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ42&geneProductId=UniProtKB:Q9NZ42)
18. [Purification and characterization of the human gamma-secretase complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ42&geneProductId=UniProtKB:Q9NZ42)
19. Ensembl Release 99