# Presenilin Dmel_CG18803

> protein found in Drosophila melanogaster

**Wikidata**: [Q29818294](https://www.wikidata.org/wiki/Q29818294)  
**Source**: https://4ort.xyz/entity/presenilin-dmel-cg18803


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O02194)
3. Q20641742
4. [An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging Drosophila Brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=O02194&geneProductId=UniProtKB:O02194)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O02194&geneProductId=UniProtKB:O02194)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
7. [The adhesion force of Notch with Delta and the rate of Notch signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=O02194&geneProductId=UniProtKB:O02194)
8. [In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
9. [The adhesion force of Notch with Delta and the rate of Notch signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
10. [An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging Drosophila Brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
11. [Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
12. [Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
13. [Drosophila Nicastrin Is Essential for the Intramembranous Cleavage of Notch](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
14. [Nicastrin Is Required for γ-Secretase Cleavage of the Drosophila Notch Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
15. [aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O02194)
16. ensembl Release 106