# premature ovarian failure

> ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40

**Wikidata**: [Q647630](https://www.wikidata.org/wiki/Q647630)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Primary_ovarian_insufficiency)  
**Source**: https://4ort.xyz/entity/premature-ovarian-failure


## References

1. Disease Ontology
2. Freebase Data Dumps. 2013
3. BBC Things
4. NDF-RT
5. Mutations in HFM1 in Recessive Primary Ovarian Insufficiency
6. Studies of FRAXA and FRAXE in women with premature ovarian failure
7. Mutant Cohesin in Premature Ovarian Failure
8. NOBOX homeobox mutation causes premature ovarian failure
9. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000106410/EFO_0004266)
10. Mutations in NR5A1 associated with ovarian insufficiency
11. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000136931/EFO_0004266)
12. Disruption of POF1B binding to nonmuscle actin filaments is associated with premature ovarian failure
13. A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: evidence for conserved function in oogenesis and implications for human sterility
14. Identification of novel mutations in FOXL2 associated with premature ovarian failure
15. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000183770/EFO_0004266)
16. Transcription factor FIGLA is mutated in patients with premature ovarian failure
17. [Identifiers.org](https://registry.identifiers.org/registry/doid)
18. Quora
19. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)