# Pre-mRNA processing factor 8

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21108689](https://www.wikidata.org/wiki/Q21108689)  
**Source**: https://4ort.xyz/entity/pre-mrna-processing-factor-8-q21108689


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q6P2Q9)
3. Q20641742
4. [The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
5. [PHF6 Interacts with the Nucleosome Remodeling and Deacetylation (NuRD) Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
6. [Death by splicing: tumor suppressor RBM5 freezes splice-site pairing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
7. [Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
8. [A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
9. [Dynamic protein-protein interaction wiring of the human spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
10. [Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
11. [The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
12. [The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2Q9&geneProductId=UniProtKB:Q6P2Q9)
14. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2Q9&geneProductId=UniProtKB:Q6P2Q9)
15. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2Q9&geneProductId=UniProtKB:Q6P2Q9)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
18. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
19. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
20. [Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2Q9&geneProductId=UniProtKB:Q6P2Q9)
21. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2Q9&geneProductId=UniProtKB:Q6P2Q9)
22. [The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2Q9&geneProductId=UniProtKB:Q6P2Q9)
23. [Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
24. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
25. [Cryo-EM structure of a human spliceosome activated for step 2 of splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
26. [Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P2Q9)
27. [The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6P2Q9&geneProductId=UniProtKB:Q6P2Q9)
28. Ensembl Release 99