# Pre-mRNA processing factor 4

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21108675](https://www.wikidata.org/wiki/Q21108675)  
**Source**: https://4ort.xyz/entity/pre-mrna-processing-factor-4-q21108675


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O43172)
3. Q20641742
4. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
5. [Identification of a PRPF4 loss-of-function variant that abrogates U4/U6.U5 tri-snRNP integration and is associated with retinitis pigmentosa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
6. [Dynamic protein-protein interaction wiring of the human spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
7. [Defining the human deubiquitinating enzyme interaction landscape](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
8. [LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
9. [The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
10. [The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
11. [RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
13. [Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
14. [The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43172&geneProductId=UniProtKB:O43172)
15. [Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43172)
16. Ensembl Release 99