# Pre-mRNA processing factor 19

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109719](https://www.wikidata.org/wiki/Q21109719)  
**Source**: https://4ort.xyz/entity/pre-mrna-processing-factor-19-q21109719


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UMS4)
3. Q20641742
4. [The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UMS4&geneProductId=UniProtKB:Q9UMS4)
5. [U box proteins as a new family of ubiquitin-protein ligases](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UMS4&geneProductId=UniProtKB:Q9UMS4)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UMS4&geneProductId=UniProtKB:Q9UMS4)
7. [U box proteins as a new family of ubiquitin-protein ligases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
8. [Molecular architecture of the human Prp19/CDC5L complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
9. [The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
10. [Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
11. [APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
12. [The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
13. [Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
14. [Dynamic protein-protein interaction wiring of the human spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
15. [Tumor suppressor RBM5 directly interacts with the DExD/H‐box protein DHX15 and stimulates its helicase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
16. [Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
17. [Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
18. [SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
21. [Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
22. [PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
23. [Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UMS4&geneProductId=UniProtKB:Q9UMS4)
24. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UMS4&geneProductId=UniProtKB:Q9UMS4)
25. [Molecular architecture of the human Prp19/CDC5L complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UMS4&geneProductId=UniProtKB:Q9UMS4)
26. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
27. [Cryo-EM structure of a human spliceosome activated for step 2 of splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
28. [Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
29. [Mouse homologue of yeast Prp19 interacts with mouse SUG1, the regulatory subunit of 26S proteasome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UMS4)
30. Ensembl Release 99