# PR/SET domain 16

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21123324](https://www.wikidata.org/wiki/Q21123324)  
**Source**: https://4ort.xyz/entity/pr-set-domain-16


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9HAZ2)
3. Q20641742
4. [SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
5. [Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
7. [A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAZ2&geneProductId=UniProtKB:Q9HAZ2)
9. [Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
10. [A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAZ2&geneProductId=UniProtKB:Q9HAZ2)
11. [Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
12. [Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
13. [Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAZ2)
14. Ensembl Release 99