# POU domain, class 5, transcription factor 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983725](https://www.wikidata.org/wiki/Q21983725)  
**Source**: https://4ort.xyz/entity/pou-domain-class-5-transcription-factor-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P20263)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
5. [Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
6. [Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
7. [A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
8. [Pluripotency factors regulate definitive endoderm specification through eomesodermin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
9. [Dax1 associates with Esrrb and regulates its function in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
10. [Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
11. [New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
12. [The octamer motif present in the Rex-1 promoter binds Oct-1 and Oct-3 expressed by EC cells and ES cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
13. [Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
14. [New type of POU domain in germ line-specific protein Oct-4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
15. [Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
16. [Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
17. [Expression of Oct-4 during differentiation of murine F9 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
18. [The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
19. [Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
20. [The embryonic Octamer factor 3/4 displays distinct DNA binding specificity from those of other Octamer factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20263&geneProductId=UniProtKB:P20263)
21. [The embryonic Octamer factor 3/4 displays distinct DNA binding specificity from those of other Octamer factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
22. [Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
23. [Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
24. [T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
25. [Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
26. [Zfp322a Regulates mouse ES cell pluripotency and enhances reprogramming efficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
27. [Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
28. [Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
29. [POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
30. [A dominant-negative form of mouse SOX2 induces trophectoderm differentiation and progressive polyploidy in mouse embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
31. [Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
32. [The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
33. [Cdk1 interplays with Oct4 to repress differentiation of embryonic stem cells into trophectoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
34. [An expanded Oct4 interaction network: implications for stem cell biology, development, and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
35. [Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
36. [Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
37. [An Oct4-centered protein interaction network in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
38. [Stimulation of Oct-4 activity by Ewing's sarcoma protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
39. [A protein interaction network for pluripotency of embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
40. [Master transcription factors determine cell-type-specific responses to TGF-β signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
41. [TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
42. [Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
43. [Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
44. [Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
45. [Deciphering the Sox-Oct partner code by quantitative cooperativity measurements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
46. [Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
47. [Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
48. [Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
49. [A unique Oct4 interface is crucial for reprogramming to pluripotency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)
50. [A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20263)