# POU class 1 homeobox 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558467](https://www.wikidata.org/wiki/Q28558467)  
**Source**: https://4ort.xyz/entity/pou-class-1-homeobox-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10037)
3. Q20641742
4. [A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin gene promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
6. [Dominant negative dimerization of a mutant homeodomain protein in Axenfeld-Rieger syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
7. [The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
8. [Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
9. [Differential utilization of transcription activation subdomains by distinct coactivators regulates Pit-1 basal and Ras responsiveness](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
10. [Repression of the prolactin promoter: a functional consequence of the heterodimerization between Pit-1 and Pit-1 beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
11. [Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10037)
12. ensembl Release 106