Potassium voltage-gated channel subfamily Q member 4
type: Thing
alternate name: potassium channel, voltage gated KQT-like subfamily Q, member 4
alternate name: potassium channel subunit alpha KvLQT4
alternate name: potassium voltage-gated channel, KQT-like subfamily, member 4
alternate name: KQT-like 4
alternate name: KCNQ4
alternate name: potassium channel KQT-like 4
alternate name: Voltage-gated potassium channel subunit Kv7.4
alternate name: potassium voltage-gated channel subfamily KQT member 4
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: ezogabine
additional property: PropertyValue
  property ID: P129
  value: bepridil
additional property: PropertyValue
  property ID: P129
  value: linopirdine
additional property: PropertyValue
  property ID: P352
  value: P56696
additional property: PropertyValue
  property ID: P361
  value: Potassium channel, voltage dependent, KCNQ4
additional property: PropertyValue
  property ID: P361
  value: KCNQ potassium channel
additional property: PropertyValue
  property ID: P361
  value: Ion transport domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Ion transport domain
additional property: PropertyValue
  property ID: P527
  value: Potassium channel, voltage dependent, KCNQ, C-terminal
additional property: PropertyValue
  property ID: P637
  value: NP_004691
additional property: PropertyValue
  property ID: P637
  value: NP_751895
additional property: PropertyValue
  property ID: P637
  value: XP_016858281
additional property: PropertyValue
  property ID: P638
  value: 2OVC
additional property: PropertyValue
  property ID: P638
  value: 4GOW
additional property: PropertyValue
  property ID: P646
  value: /m/03gyfcd
additional property: PropertyValue
  property ID: P680
  value: potassium channel activity
additional property: PropertyValue
  property ID: P680
  value: voltage-gated ion channel activity
additional property: PropertyValue
  property ID: P680
  value: ion channel activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: voltage-gated potassium channel complex
additional property: PropertyValue
  property ID: P682
  value: regulation of ion transmembrane transport
additional property: PropertyValue
  property ID: P682
  value: ion transport
additional property: PropertyValue
  property ID: P682
  value: hearing
additional property: PropertyValue
  property ID: P702
  value: KCNQ4
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000262916
additional property: PropertyValue
  property ID: P705
  value: ENSP00000423756
additional property: PropertyValue
  property ID: P705
  value: ENSP00000406735
confidence:
  popularity graph score:
    score: 0.008
    score pct: 1
    tier: established
    components:
      sitelinks: 7
      sitelinks norm: 0.017
      unique citations: 15
      unique citations norm: 0.006
      monthly pageviews: 15
      monthly pageviews norm: 0.0
  sitelinks: 7
  unique citations: 15
  monthly pageviews: 15
  yearly pageviews: 28
  pageview trend:
    m: 2026-07
    v: 15
  pageview trend:
    m: 2026-06
    v: 6
  pageview trend:
    m: 2026-05
    v: 1
  pageview trend:
    m: 2026-04
    v: 5
  pageview trend:
    m: 2026-04
    v: 1
  popularity:
    sitelinks: 7
    max: 423
    pct: 1.7
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q2146170
    source count: 1
    confidence: 0.2
    value label: ezogabine
  P129:
    value: Q4890934
    source count: 1
    confidence: 0.2
    value label: bepridil
  P129:
    value: Q6554730
    source count: 1
    confidence: 0.2
    value label: linopirdine
  P129:
    value: Q410728
    source count: 1
    confidence: 0.2
    value label: tetraethylammonium
  P129:
    value: Q183309
    source count: 1
    confidence: 0.2
    value label: guanidine
  P352:
    value: P56696
    source count: 1
    confidence: 0.2
  P361:
    value: Q24780560
    source count: 1
    confidence: 0.2
    value label: Potassium channel, voltage dependent, KCNQ4
  P361:
    value: Q74805923
    source count: 1
    confidence: 0.2
    value label: KCNQ potassium channel
  P361:
    value: Q83138248
    source count: 1
    confidence: 0.2
    value label: Ion transport domain, protein family
  P361:
    value: Q83135350
    source count: 1
    confidence: 0.2
    value label: Potassium channel, voltage dependent, KCNQ, C-terminal domain, protein family
  P527:
    value: Q24767982
    source count: 1
    confidence: 0.2
    value label: Ion transport domain
  P527:
    value: Q24725775
    source count: 1
    confidence: 0.2
    value label: Potassium channel, voltage dependent, KCNQ, C-terminal

value: NP_004691
source count: 1
confidence: 0.2

value: NP_751895
source count: 1
confidence: 0.2

value: XP_016858281
source count: 1
confidence: 0.2

value: 2OVC
source count: 1
confidence: 0.2

value: 4GOW
source count: 1
confidence: 0.2

value: /m/03gyfcd
source count: 0
confidence: 0.0

value: Q14865153
source count: 2
confidence: 0.4
value label: potassium channel activity

value: Q14865152
source count: 1
confidence: 0.2
value label: voltage-gated ion channel activity

value: Q14864714
source count: 1
confidence: 0.2
value label: ion channel activity

value: Q167149
source count: 2
confidence: 0.4
value label: protein binding

value: Q14593999
source count: 3
confidence: 0.6
value label: voltage-gated potassium channel activity

value: Q14327652
source count: 2
confidence: 0.4
value label: integral component of membrane

value: Q14349455
source count: 2
confidence: 0.4
value label: membrane

value: Q14594609
source count: 1
confidence: 0.2
value label: voltage-gated potassium channel complex

value: Q29548
source count: 2
confidence: 0.4
value label: plasma membrane

value: Q14860541
source count: 1
confidence: 0.2
value label: basal plasma membrane

value: Q14865155
source count: 1
confidence: 0.2
value label: regulation of ion transmembrane transport

value: Q14859673
source count: 2
confidence: 0.4
value label: ion transport

value: Q160289
source count: 3
confidence: 0.6
value label: hearing

value: Q14860315
source count: 4
confidence: 0.8
value label: potassium ion transport

value: Q14820680
source count: 1
confidence: 0.2
value label: transmembrane transport

value: Q18033856
source count: 1
confidence: 0.2
value label: KCNQ4

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000262916
source count: 1
confidence: 0.2

value: ENSP00000423756
source count: 1
confidence: 0.2

value: ENSP00000406735
source count: 1
confidence: 0.2

value: 188357236
source count: 0
confidence: 0.0

value: 1.A.1.15.4
source count: 2
confidence: 0.4

source: Open Targets Platform
stated in qid: Q113138000
retrieved: 2023-08-14

source: Open Targets Platform
stated in qid: Q113138000
retrieved: 2023-08-14

source: Open Targets Platform
stated in qid: Q113138000
retrieved: 2023-08-14

source: KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness
stated in qid: Q22008780
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits
stated in qid: Q24336294
retrieved: 2019-04-08

source: Distinct Roles of Molecular Chaperones HSP90α and HSP90β in the Biogenesis of KCNQ4 Channels
stated in qid: Q28115218
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-03-27

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21108785
domain: protein
level: standard
html url: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-q-member-4
markdown url: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-q-member-4.md
facts url summary: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-q-member-4/facts.json
facts url standard: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-q-member-4/facts.json
facts url full: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-q-member-4/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T00:00:02.260702Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-04-10T23:40:11.929560+00:00Z