Potassium voltage-gated channel subfamily E regulatory subunit 5
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Potassium channel, voltage-dependent, beta subunit, KCNE
additional property: PropertyValue
  property ID: P637
  value: NP_036414
additional property: PropertyValue
  property ID: P680
  value: transmembrane transporter binding
additional property: PropertyValue
  property ID: P680
  value: voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
additional property: PropertyValue
  property ID: P680
  value: potassium channel regulator activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: voltage-gated potassium channel complex
additional property: PropertyValue
  property ID: P682
  value: regulation of atrial cardiac muscle cell membrane repolarization
additional property: PropertyValue
  property ID: P682
  value: regulation of heart contraction
additional property: PropertyValue
  property ID: P682
  value: cardiac muscle contraction
additional property: PropertyValue
  property ID: P702
  value: KCNE5
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000361173
additional property: PropertyValue
  property ID: P7260
  value: 8.A.10.3.2
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 14
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 14
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9UJ90
    source count: 1
    confidence: 0.2
  P361:
    value: Q24774918
    source count: 1
    confidence: 0.2
    value label: Potassium channel, voltage-dependent, beta subunit, KCNE
  P637:
    value: NP_036414
    source count: 1
    confidence: 0.2
  P680:
    value: Q14901685
    source count: 1
    confidence: 0.2
    value label: transmembrane transporter binding
  P680:
    value: Q14905750
    source count: 1
    confidence: 0.2
    value label: voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
  P680:
    value: Q14594005
    source count: 3
    confidence: 0.6
    value label: potassium channel regulator activity
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14593999
    source count: 2
    confidence: 0.4
    value label: voltage-gated potassium channel activity
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q14349455
    source count: 2
    confidence: 0.4
    value label: membrane
  P681:
    value: Q14594609
    source count: 2
    confidence: 0.4
    value label: voltage-gated potassium channel complex
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P681:
    value: Q14594609
    source count: 3
    confidence: 0.6
    value label: voltage-gated potassium channel complex
  P682:
    value: Q14905720
    source count: 1
    confidence: 0.2
    value label: regulation of atrial cardiac muscle cell membrane repolarization
  P682:
    value: Q14860525
    source count: 1
    confidence: 0.2
    value label: regulation of heart contraction
  P682:
    value: Q14864283
    source count: 1
    confidence: 0.2
    value label: cardiac muscle contraction
  P682:
    value: Q14901703
    source count: 1
    confidence: 0.2
    value label: ventricular cardiac muscle cell action potential
  P682:
    value: Q14859673
    source count: 1
    confidence: 0.2
    value label: ion transport
  P702:
    value: Q18037551
    source count: 1
    confidence: 0.2
    value label: KCNE5
  P703:
    value: Q15978631
    source count: 1
    confidence: 0.2
    value label: Homo sapiens
  P705:
    value: ENSP00000361173
    source count: 1
    confidence: 0.2
  P7260:
    value: 8.A.10.3.2
    source count: 2
    confidence: 0.4
citations:
  source: KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current
  stated in qid: Q24307743
  retrieved: 2018-03-27
citations:
  source: KCNE5 ( KCNE1L ) Variants Are Novel Modulators of Brugada Syndrome and Idiopathic Ventricular Fibrillation
  stated in qid: Q24299782
  retrieved: 2019-04-08
citations:
  source: KCNE5 ( KCNE1L ) Variants Are Novel Modulators of Brugada Syndrome and Idiopathic Ventricular Fibrillation
  stated in qid: Q24299782
  retrieved: 2018-03-27
citations:
  source: Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation
  stated in qid: Q24320049
  retrieved: 2018-03-27
citations:
  source: Impact of KCNE subunits on KCNQ1 (Kv7.1) channel membrane surface targeting
  stated in qid: Q24318425
  retrieved: 2019-04-08
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-04-08

source: KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current
stated in qid: Q24307743
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation
stated in qid: Q24320049
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21119854
domain: protein
level: standard
html url: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-e-regulatory-subunit-5
markdown url: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-e-regulatory-subunit-5.md
facts url summary: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-e-regulatory-subunit-5/facts.json
facts url standard: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-e-regulatory-subunit-5/facts.json
facts url full: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-e-regulatory-subunit-5/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-13T13:17:09.978542Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:40:42.669745+00:00Z