# Potassium voltage-gated channel subfamily A member 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21096394](https://www.wikidata.org/wiki/Q21096394)  
**Source**: https://4ort.xyz/entity/potassium-voltage-gated-channel-subfamily-a-member-5-q21096394


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL821)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P22460)
5. Q20641742
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
7. [Acute hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
8. [Different isoforms of synapse-associated protein, SAP97, are expressed in the heart and have distinct effects on the voltage-gated K+ channel Kv1.5](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
10. [Different isoforms of synapse-associated protein, SAP97, are expressed in the heart and have distinct effects on the voltage-gated K+ channel Kv1.5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
11. [Four and a half LIM protein 1: a partner for KCNA5 in human atrium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
12. [Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
13. [Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
14. [Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
15. [Modulation of the human Kv1.5 channel by protein kinase C activation: role of the Kvbeta1.2 subunit](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
16. [Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
17. [Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
18. [alpha-actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
19. [A discrete amino terminal domain of Kv1.5 and Kv1.4 potassium channels interacts with the spectrin repeats of alpha-actinin-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
20. [Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
22. [Modulation of the human Kv1.5 channel by protein kinase C activation: role of the Kvbeta1.2 subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
23. [Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
24. [Acute hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
25. [Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
26. [Localization of the Kv1.5 K+ channel protein in explanted cardiac tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
27. [Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
28. [Localization of the Kv1.5 K+ channel protein in explanted cardiac tissue](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22460&geneProductId=UniProtKB:P22460)
29. [Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
30. [Kv1.5 association modifies Kv1.3 traffic and membrane localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
31. [Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
32. [Amino-terminal determinants of U-type inactivation of voltage-gated K+ channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
33. [Functional differences in Kv1.5 currents expressed in mammalian cell lines are due to the presence of endogenous Kv beta 2.1 subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
34. [Presence of the Kv1.5 K(+) channel in the sinoatrial node](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22460)
35. Ensembl Release 99
36. UMLS 2023
37. Transporter Classification database